Bone Marrow Oxalosis in a Two Year Old Child with Congenital Hypoplastic Kidneys – A Case Report
Keywords:Oxalosis, bone marrow, congenital hypoplastic kidneys
Oxalate deposition in different extra-renal tissues resulting in systemic involvement is called as systemic oxalosis. The urinary tract, including renal parenchyma, is the first deposition site followed by extra-renal organs, for instance, bone marrow. Bone marrow oxalosis is described by hepatosplenomegaly, deranged cell lines, i.e., cytopenias, leukoerythroblastosis, and calcium oxalate crystals in bone marrow biopsy. We are reporting a case of a 2 years old child with Chronic Kidney Disease and a history of congenital hypoplastic kidneys. The patient had mild pallor and features of renal osteodystrophy at the time of presentation. A bone marrow biopsy was performed that showed interstitial deposition of oxalate crystals and preserved trilineage hematopoietic constituents in the absence of peripheral cytopenias.
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