Epidemiological Profile of Patients with Hemophilia in Northern Pakistan: A Single-Center Study

Abstract

Objective: To study the epidemiological profile of patients with haemophilia in northern Pakistan.

Methodology: This research was cross-sectional and observational. Investigations were conducted on hemophiliac patients of various ages who had registered with the Hemophilia Patients Welfare Society in Rawalpindi. A thorough clinical and epidemiological history was gathered from the patient or the patient's accompanying parent or guardian using a pre-structured questionnaire. In accordance with test results and factor VIII and IX assay levels, patients were further divided into mild, moderate, and severe groups.

Results: One female patient of Hemophilia B is one of the important findings of this study. 0ut of total 837 patients investigated, 702 were of Hemophilia A and 135 were of Hemophilia B. 46.47% (389/837) belongs to the age group of >17 years. 476 (56.86%) were severe hemophiliacs, 269 (32.15%) were moderate and 92 (bn 10.99%) were mild hemophilia patients. Knee was the most involved joint and it was observed in 331 (39.57%) patients.

Conclusion: The most common type of hemophilia is the severe form of hemophilia a (classic hemophilia). This study also found a female hemophilia B case which is the novel identification of this study. It is concluded that there is a need to start a national level diagnosis, prevention and care program for hemophilia patients.