Mean Platelet Volume in Patients of Acute Coronary Syndrome

Abstract

Objective: The purpose of our study was to assess the accuracy of elevated mean platelet volume (MPV) as an independent diagnostic marker for acute coronary syndrome (ACS).

Methodology: This descriptive cross-sectional study was conducted in the Department of Hematology in collaboration with the Department of Cardiology (CCU) at Fauji Foundation Hospital Rawalpindi, from December 2017 to June 2018. The Coronary Care Unit (CCU) records of 100 ACS patients admitted to FFH Rawalpindi were reviewed. All collected data were entered into SPSS version 17. Mean and standard deviation were calculated for quantitative variables, such as MPV and age. An independent sample t-test was used to compare effect modifiers like age and gender, with statistical significance set at p<0.05.

Results: A total of 100 patients were enrolled, with a mean age of 57.06±9.95 years for males and 56.0±9.48 years for females. There were 17 (17%) male and 83 (83%) female patients. The mean platelet volume was found to be higher among ACS patients (10.736±0.89 fl). The mean MPV in patients aged ?55 years was 10.63±0.97, while in patients aged >55 years it was 10.82±0.81. The mean MPV for male patients was 10.44±0.72, and for female patients, it was 10.80±0.91. No significant difference was observed in mean MPV between genders or age groups (p>0.05).

Conclusion: The study concluded that MPV significantly increases in patients with acute coronary syndrome and may serve as a potential diagnostic marker in such patients.