Successful Outcome of Pregnancy in Bernard -Soulier Syndrome with Temporary Endovascular Balloon Occlusion of Uterine Arteries: A Case Report

Abstract

An uncommon congenital bleeding illness known as Bernard-Soulier Syndrome (BSS) is primarily inherited in an autosomal recessive pattern. Depending on the individual mutation, the phenotype of BSS varies significantly. There is no consensus on the best treatment for patients with BSS, and pregnancy is linked to a high risk of bleeding for both the mother and the newborn. The use of perioperative endovascular balloon occlusion of the internal iliac arteries (uterine artery) is a minimally invasive technique that reduces blood loss and the need for transfusions in high bleeding risk patients, such as those with BSS.

This case describes a successful pregnancy outcome with endovascular intervention in a woman with BSS who was closely monitored during pregnancy, the peripartum period, and the postpartum period, and who had a planned birth. Minimally invasive and effective endovascular prophylactic measures against bleeding reduce blood loss, the need for transfusions, platelet refractoriness, and hospital stay during a cesarean section in patients with BSS.